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Selected bioinformatic techniques

Some basic information about the module

Cycle of education: 2022/2023

The name of the faculty organization unit: The faculty Chemistry

The name of the field of study: Biotechnology

The area of study: technical sciences

The profile of studing:

The level of study: second degree study

Type of study: full time

discipline specialities : Laboratory diagnostics in biotechnology, Pharmaceutical biotechnology, Process and bioprocess engineering, Purification and analysis of biotechnological products

The degree after graduating from university: Master of Science (MSc)

The name of the module department : Department of Biochemistry and Bioinformatics

The code of the module: 5230

The module status: mandatory for the speciality Process and bioprocess engineering

The position in the studies teaching programme: sem: 2 / W15 L15 / 2 ECTS / Z

The language of the lecture: Polish

The name of the coordinator 1: Barbara Dębska, DSc, PhD, Eng.

The name of the coordinator 2: Grzegorz Fic, PhD, Eng.

The aim of studying and bibliography

The main aim of study: Gain knowledge and skills in computer-aided research in biotechnology

The general information about the module: The module is realized in the form of lectures (15h) and problem exercises in computer laboratory (15 h)

Teaching materials: Materiały dydaktyczne dostepne on-line w portalu ZICh PRz oraz www.e-chemia.pl

Bibliography required to complete the module
Bibliography used during lectures
1 T. Stubblebine Wyrażenia regularne. Leksykon kieszonkowy Helion. 2008
2 R. L. Schwartz, T. Phoenix, B. d foy Perl. Wprowadzenie Helion. 2006
3 B.Dębska, G.Fic Konspekty do wykładów opublikowane na stronie Zakładu Informatyki Chemicznej ZICh PRz. 2012
Bibliography used during classes/laboratories/others
1 B. Dębska, G. Fic Bioinformatyka II. Instrukcje do ćwiczeń laboratoryjnych ZICh PRz. 2012
Bibliography to self-study
1 A. D. Baxevanis, B. F. F. Ouellette Bioinformatyka . Podręcznik do analizy genów i białek PWN Warszawa. 2004
2 P. G. Higgs, T. K. Attwood Bioinformatyka i ewolucja molekularna PWN Warszawa. 2008
3 J.Xiong Podstawy bioinformatyki Wydawnictwa Uniwersytetu Warszawskiego. 2009

Basic requirements in category knowledge/skills/social competences

Formal requirements:

Basic requirements in category knowledge: basic knowledge of biochemistry, molecular biology

Basic requirements in category skills: computer skills - Windows, search for information in the biological and chemical databases

Basic requirements in category social competences: Ability to work individually and in a team of 2-3 persons.

Module outcomes

MEK The student who completed the module Types of classes / teaching methods leading to achieving a given outcome of teaching Methods of verifying every mentioned outcome of teaching Relationships with KEK Relationships with PRK
01 can test and modify computer programs in Perl to solve simple problems in molecular biology and biotechnology lecture, laboratory test, observation of the task performance, project report, K_W02++
K_W06+
K_U07++
P7S_UW
P7S_WG
02 knows the basics of programming in Perl lecture, laboratory test, observation of the task performance, project report K_W02++
K_U07++
P7S_UW
P7S_WG
03 is able to use specialized computer programs for searching and for analysis of sequential information. laboratory test, observation of the task performance, project report K_W02++
K_W06++
K_U01+
K_U07++
P7S_UW
P7S_WG
04 can use the selected artificial intelligence methods to support engineering tasks and scientific research in the field of molecular biology and biotechnology lecture, laboratory test, written report K_W02+++
K_W06+
K_U07++
P7S_UW
P7S_WG

Attention: Depending on the epidemic situation, verification of the achieved learning outcomes specified in the study program, in particular credits and examinations at the end of specific classes, can be implemented remotely (real-time meetings).

The syllabus of the module

Sem. TK The content realized in MEK
2 TK01 Artificial intelligence techniques in bioinformatics. Artificial neural networks W01 MEK04
2 TK02 Graph theory and decision trees. Methods of presentation and interpretation of decision trees. Methods for generating phylogenetic trees W02 MEK03 MEK04
2 TK03 Sequence similarity searching. Sequence matching algorithms W03-W04 MEK03
2 TK04 Beginner’s introduction to PERL Programming Language. Perl in bioinformatics W05-W06 MEK01 MEK02
2 TK05 Regular expression and their application in bioinformatics W07 MEK01 MEK02
2 TK06 Sequence similarity searching. L01 MEK03
2 TK07 PERL programming language in molecular biology L03-L05 MEK01 MEK02
2 TK08 Genetic and physical maps L02 MEK03

The student's effort

The type of classes The work before classes The participation in classes The work after classes
Lecture (sem. 2) contact hours: 15.00 hours/sem.
complementing/reading through notes: 2.00 hours/sem.
Studying the recommended bibliography: 2.00 hours/sem.
Laboratory (sem. 2) The preparation for a Laboratory: 5.00 hours/sem.
The preparation for a test: 5.00 hours/sem.
contact hours: 15.00 hours/sem.
Finishing/Making the report: 5.00 hours/sem.
Advice (sem. 2) The participation in Advice: 2.00 hours/sem.
Credit (sem. 2) The preparation for a Credit: 3.00 hours/sem.
The written credit: 2.00 hours/sem.

The way of giving the component module grades and the final grade

The type of classes The way of giving the final grade
Lecture
Laboratory Credit all the laboratory (test, execution of exercises, report)
The final grade Final grade (K): K= 0.5w L +0.5wW, L- positive evaluation of the lab; W - positive evaluation of the lecture, w - factor related to the time of credit, w= 1,0 first term, w = 0,9 second term , w = 0,8 third term.

Sample problems

Required during the exam/when receiving the credit
(-)

Realized during classes/laboratories/projects
(-)

Others
(-)

Can a student use any teaching aids during the exam/when receiving the credit : no

The contents of the module are associated with the research profile: yes

1 J. Buczkowicz; T. Drzazga; G. Fic; M. Jaromin; P. Krajewski; P. Matysik; R. Mazur; P. Milczarski; T. Sikora; M. Szeliga; D. Tyrka; M. Tyrka; E. Witkowski Selekcja genomowa pszenicy ozimej 2021
2 B. Dębska; B. Dębska; L. Lichołai Evaluation of the Utility of Using Classification Algorithms when Designing New Polymer Composites 2019
3 B. Dębska; J. Duliban; K. Hęclik; J. Lubczak Analysis of the Possibility and Conditions of Application of Methylene Blue to Determine the Activity of Radicals in Model System with Preaccelerated Cross-Linking of Polyester Resins 2019
4 B. Dębska; L. Dobrowolski; M. Inger; M. Jaromin; M. Wilk Komputerowo-wspomagane obliczanie bilansu masowego i cieplnego instalacji chemicznej 2019