The aim of studying and bibliography

The main aim of study: Gain knowledge and skills in computer-aided research in biotechnology

The general information about the module:

Teaching materials: B.Dębska, G.Fic Instrukcje do ćwiczeń laboratoryjnych, Portal ZICh PRz

Bibliography required to complete the module

Bibliography used during classes/laboratories/others

1	B. Dębska, G. Fic	Bioinformatyka. Materiały dydaktyczne do wykładów, dostęp on-line	http://www.prz.rzeszow.pl/chemia/zich.	2014
2	G. Fic	Komputerowe wspomaganie badań. Materiały dydaktyczne i instrukcje do ćwiczeń, dostęp on-line	http://www.prz.rzeszow.pl/chemia/zich.	2014

Bibliography to self-study

1	A. D. Baxevanis, B. F. F. Ouellette	Bioinformatyka . Podręcznik do analizy genów i białek	PWN Warszawa.	2004
2	P. G. Higgs, T. K. Attwood	Bioinformatyka i ewolucja molekularna	PWN Warszawa.	2008
3	J.Xiong	Podstawy bioinformatyki	Wydawnictwa Uniwersytetu Warszawskiego.	2009

Basic requirements in category knowledge/skills/social competences

Formal requirements: Registration for the semester

Basic requirements in category knowledge: basic knowledge of organic chemistry and biochemistry

Basic requirements in category skills: computer skills - Windows

Basic requirements in category social competences: Ability to work individually and in a team of 2-3 persons.

Module outcomes

MEK	The student who completed the module	Types of classes / teaching methods leading to achieving a given outcome of teaching	Methods of verifying every mentioned outcome of teaching	Relationships with KEK	Relationships with PRK
01	is able to efficiently search for and retrieve information from chemical and biological databases.	laboratory, e-learning	test, written report	K_W03++ K_U01++ K_U08+++	P6S_UW P6S_WG
02	is able to predict biodegradation pathways for chemical compounds	laboratory, e-learning	written report	K_W03+++ K_U06++ K_U08++	P6S_UU P6S_UW P6S_WG
03	is able to predict biological and chemical properties of chemical compounds and proteins	laboratory, e-learning	test, written report	K_W03++ K_U08++	P6S_UW P6S_WG

Attention: Depending on the epidemic situation, verification of the achieved learning outcomes specified in the study program, in particular credits and examinations at the end of specific classes, can be implemented remotely (real-time meetings).

The syllabus of the module

Sem.	TK	The content	realized in	MEK
5	TK01	Strategies of searching chemical structures and metabolic databases	L02	MEK01
5	TK02	Chemical structure formats. 3D visualization of chemical structures	L01	MEK01
5	TK03	CAOS - computer prediction of biodegradation pathways for chemical compounds and generation of combinatorial libraries	L03	MEK02
5	TK04	Computer design of new drugs	L05	MEK03
5	TK05	Chemical similarity	L04	MEK03

The student's effort

The type of classes	The work before classes	The participation in classes	The work after classes
Laboratory (sem. 5)	The preparation for a Laboratory: 5.00 hours/sem. The preparation for a test: 5.00 hours/sem.	contact hours: 15.00 hours/sem.	Finishing/Making the report: 2.00 hours/sem.
Advice (sem. 5)
Credit (sem. 5)		The written credit: 1.00 hours/sem.

The way of giving the component module grades and the final grade

The type of classes	The way of giving the final grade
Laboratory
The final grade	Final grade (K): K= w L, L- positive evaluation of the lab; w - factor related to the time of credit, w= 1,0 first term, w = 0,9 second term , w = 0,8 third term.

Sample problems

Required during the exam/when receiving the credit
(-)

Realized during classes/laboratories/projects
(-)

Others
(-)

Can a student use any teaching aids during the exam/when receiving the credit : no

The contents of the module are associated with the research profile: yes

1	A. Czerniecka-Kubicka; L. Dobrowolski; K. Hęclik; I. Zarzyka	Kompozyt polimerowy oraz sposób wytwarzania kompozytu polimerowego	2024
2	L. Dobrowolski; K. Hęclik; M. Jaromin; I. Zarzyka	A Practical Test of Distance Learning During the COVID-19 Lockdown	2023
3	M. Bakar; A. Białkowska; A. Czerniecka-Kubicka; L. Dobrowolski; K. Hęclik; B. Krzykowska; M. Longosz; I. Zarzyka	Polymer Biocompositions and Nanobiocomposites Based on P3HB with Polyurethane and Montmorillonite	2023
4	M. Chmiela; A. Czerniecka-Kubicka; L. Dobrowolski; W. Gonciarz; K. Hęclik; M. Longosz; A. Szyszkowska; D. Trzybiński; K. Woźniak; A. Wróbel; I. Zarzyka	Molecular Modeling of 3-chloro-3-phenylquinoline-2,4-dione, Crystal Structure and Cytotoxic Activity for developments in a potential new drug	2023
5	K. Hęclik; M. Jacquet; J. Kargul; S. Kozdra; P. Michałowski; A. Wójcik	Insight into structure-property relationship of organometallic terpyridine wires: Combined theoretical and experimental study	2022
6	M. Bakar; A. Białkowska; A. Czerniecka-Kubicka; L. Dobrowolski; K. Hęclik; B. Krzykowska; I. Zarzyka	Biobased poly(3-hydroxybutyrate acid) composites with addition of aliphatic polyurethane based on polypropylene glycols	2022
7	K. Hęclik; K. Hęclik; I. Zarzyka	Metal-Humus Acid Nanoparticles - Synthesis, Characterization and Molecular Modeling	2021
8	M. Bakar; A. Białkowska; A. Czerniecka-Kubicka; L. Dobrowolski; K. Hęclik; K. Leś; M. Pyda; M. Walczak; I. Zarzyka	Thermally stable biopolymer composites based on poly(3-hydroxybutyrate) modified with linear aliphatic polyurethanes – preparation and properties	2021
9	A. Czerniecka-Kubicka; L. Dobrowolski; K. Hęclik; I. Zarzyka	Biodegradowalne kompozyty polimerowe na osnowie P3HB	2020
10	R. Bartosik; L. Dobrowolski; K. Hęclik; A. Klasek; A. Lycka; I. Zarzyka	New mono- and diesters with imidazoquinolinone ring- synthesis, structure characterization and molecular modeling	2020
11	B. Dębska; J. Duliban; K. Hęclik; J. Lubczak	Analysis of the Possibility and Conditions of Application of Methylene Blue to Determine the Activity of Radicals in Model System with Preaccelerated Cross-Linking of Polyester Resins	2019
12	K. Hęclik; A. Klasek; S. Pawlędzio; A. Szyszkowska; D. Trzybiński; K. Woźniak; I. Zarzyka	Unprecedented reaction course of 1-phenyl-2H,6H-imidazo[1,5-c]quinazoline-3,5-dione with an excess of ethylene oxide	2019
13	K. Hęclik; A. Szyszkowska; I. Zarzyka	Spatial packing of diols and esters with imidazoquinazoline ring - quantum-mechanical modelling	2019