Cycle of education: 2022/2023
The name of the faculty organization unit: The faculty Chemistry
The name of the field of study: Biotechnology
The area of study: technical sciences
The profile of studing:
The level of study: first degree study
Type of study: full time
discipline specialities : Applied biochemistry, Purification and analysis of biotechnological products
The degree after graduating from university: Bachelor of Science (BSc)
The name of the module department : Department of Physical Chemistry
The code of the module: 248
The module status: mandatory for the speciality Purification and analysis of biotechnological products
The position in the studies teaching programme: sem: 6 / W30 L15 P30 / 6 ECTS / Z
The language of the lecture: Polish
The name of the coordinator 1: Katarzyna Rydel-Ciszek, PhD, Eng.
office hours of the coordinator: Poniedziałek 12:00-14:00, Wtorek 12:00-14:00
The name of the coordinator 2: Prof. Paweł Chmielarz, DSc, PhD, Eng.
office hours of the coordinator: Poniedziałek 12:00-14:00, Piątek 12:00-14:00
The main aim of study: Introducing the students to modern methods and computational tools used in biomolecular modeling. This knowledge is essential for studying of biotechnology processes (eg. conformation analysis, study of dynamic properties of biomolecules, designing new compounds, etc.).
The general information about the module: The module is implemented in the sixth semester. It includes 30 hours of lectures, 15 hours of laboratory and 30 hours of project. The module is ending with the credit.
Teaching materials: Instrukcje do ćwiczeń laboratoryjnych dostępne ze strony domowej koordynatora
1 | L. Piela | Idee chemii kwantowej | PWN, Warszawa. | 2003 |
2 | W. Kołos, J. Sadlej | Atom i cząsteczka | WNT Warszawa. | 1998 |
3 | A.D. Baxevanis, B.F.F. Quellette | Bioinformatyka. Podręcznik do analizy genów i białek | PWN, Warszawa. | 2005 |
4 | P. G. Higgs, T. K. Attwood | Bioinformatyka i ewolucja molekularna | PWN, Warszawa. | 2008 |
1 | T.Pietryga | Instrukcje laboratoryjne | Katedra Chemii Fizycznej. | 2012 |
Formal requirements: Registration for the given semester
Basic requirements in category knowledge: Basic knowledge in the physical chemistry, biochemistry and proteins
Basic requirements in category skills: Basic computer skills.
Basic requirements in category social competences: Ability of the cooperation and the work in the group
MEK | The student who completed the module | Types of classes / teaching methods leading to achieving a given outcome of teaching | Methods of verifying every mentioned outcome of teaching | Relationships with KEK | Relationships with PRK |
---|---|---|---|---|---|
01 | Has a basic knowledge of: -the methods of molecular and biomolecular modelling; -modeling of simple chemical reactions, spectroscopic spectra and ligand-receptor interactions; -prediction of secondary protein structure and space protein structure; -biomolecular data bases and homological analysis of protein; -structure-activity relatioships (QSAR). | lecture, laboratory | written test, written report |
K_W03++ K_W14++ |
P6S_WG |
02 | Is able to apply basic methods of biomolecular modeling to study simple chemical reactions and to predict reactivity/activity of chemical compounds based on their structure and to estimate heat effects of simple chemical processes. Is able to model a simple biotechnological process using tools of biomolecular modeling. | laboratory, team project (2) | written raport, raport from the project |
K_U08++ K_U19++ K_K03++ |
P6S_KR P6S_UO P6S_UW |
03 | Is able to find pieces of information in literature data bases and biomolecular data bases. | laboratory, team (2) project | written raport, raport from the project |
K_U01++ |
P6S_UW |
04 | Is aware that biomolecular modeling process can be multivariant one and therefore is able to work alone and collectively, make decisions and follow instructions of superiors, responsible for the research. Is also aware of the fact that biomolecular modeling methods are constantly developing and understands the necessity of additional training and improving ones professional qualifications in this | lecture, laboratory, team (2) project | written test, written report |
K_K01+ K_K03+ |
P6S_KK P6S_KR |
Attention: Depending on the epidemic situation, verification of the achieved learning outcomes specified in the study program, in particular credits and examinations at the end of specific classes, can be implemented remotely (real-time meetings).
Sem. | TK | The content | realized in | MEK |
---|---|---|---|---|
6 | TK01 | W30 | MEK01 | |
6 | TK02 | L15 | MEK02 MEK03 MEK04 | |
6 | TK03 | P30 | MEK02 MEK03 MEK04 |
The type of classes | The work before classes | The participation in classes | The work after classes |
---|---|---|---|
Lecture (sem. 6) | contact hours:
30.00 hours/sem. |
complementing/reading through notes:
2.00 hours/sem. Studying the recommended bibliography: 15.00 hours/sem. |
|
Laboratory (sem. 6) | The preparation for a Laboratory:
5.00 hours/sem. |
contact hours:
15.00 hours/sem. |
Finishing/Making the report:
5.00 hours/sem. |
Project/Seminar (sem. 6) | The preparation for projects/seminars:
15.00 hours/sem. |
contact hours:
30.00 hours/sem.. |
Doing the project/report/ Keeping records:
15.00 hours/sem. |
Advice (sem. 6) | The participation in Advice:
3.00 hours/sem. |
||
Credit (sem. 6) | The preparation for a Credit:
15.00 hours/sem. |
The written credit:
1.00 hours/sem. |
The type of classes | The way of giving the final grade |
---|---|
Lecture | Written credit of lecture covering the entire range of material of lecture. Evaluation of the test depends on the number of points scored: 3,0 (50,0 %-60,0%) MP ; 3,5 (60,1%-70,0%) MP; 4,0 (70,1%-80,0%) MP; 4,5 (80,1%-90,0%) MP; 5,0 (90,1%-100%) MP. MP- max. points. |
Laboratory | Correct performance of laboratory exercises included in the schedule and correct preparation of written reports on every exercise. |
Project/Seminar | Carrying out of a computational design, submission of written report on the project and its positive evaluation. |
The final grade | Final grade (K): K = 0,50 w W + 0,50 w P; where: W, P - positive evaluation of the credit of lecture, project; w - factor related to the time of credit or project, w= 1.0 first term, w = 0.9 second term , w = 0.8 third term.The grade is rounded according to WKZJK. |
Required during the exam/when receiving the credit
(-)
Realized during classes/laboratories/projects
(-)
Others
(-)
Can a student use any teaching aids during the exam/when receiving the credit : no
1 | K. Awsiuk; J. Bała; P. Chmielarz; E. Ciszkowicz; J. Raczkowska; M. Sroka; K. Wolski; I. Zaborniak | Grafting of Multifunctional Polymer Brushes from a Glass Surface: Surface-Initiated Atom Transfer Radical Polymerization as a Versatile Tool for Biomedical Materials Engineering | 2024 |
2 | K. Awsiuk; P. Chmielarz; M. Flejszar; N. Janiszewska; J. Raczkowska; K. Spilarewicz; K. Ślusarczyk; K. Wolski; M. Wytrwal | On the way to increase osseointegration potential: Sequential SI-ATRP as promising tool for PEEK-based implant nano-engineering | 2024 |
3 | K. Rydel-Ciszek | DFT Studies of the Activity and Reactivity of Limonene in Comparison with Selected Monoterpenes | 2024 |
4 | P. Błoniarz; P. Chmielarz; K. Kisiel; M. Klamut; K. Matyjaszewski; M. Niemiec; A. Pellis; C. Warne; I. Zaborniak | Controlled Polymer Synthesis Toward Green Chemistry: Deep Insights into Atom Transfer Radical Polymerization in Biobased Substitutes for Polar Aprotic Solvents | 2024 |
5 | G. Bartosz; P. Chmielarz; A. Dziedzic; N. Pieńkowska; I. Sadowska-Bartosz; I. Zaborniak | Nitroxide-containing amphiphilic polymers prepared by simplified electrochemically mediated ATRP as candidates for therapeutic antioxidants | 2023 |
6 | G. Bartosz; P. Chmielarz; M. Fahnestock; C. Mahadeo; N. Pieńkowska; I. Sadowska-Bartosz; I. Zaborniak | Induction of Oxidative Stress in SH-SY5Y Cells by Overexpression of hTau40 and Its Mitigation by Redox-Active Nanoparticles | 2023 |
7 | K. Awsiuk; P. Chmielarz; M. Flejszar; A. Hochół; J. Raczkowska; K. Spilarewicz; K. Ślusarczyk; K. Wolski; M. Wytrwal | Sequential SI-ATRP in μL-scale for surface nanoengineering: A new concept for designing polyelectrolyte nanolayers formed by complex architecture polymers | 2023 |
8 | P. Błoniarz; P. Chmielarz; M. Flejszar; A. Hochół; K. Spilarewicz; K. Ślusarczyk | Replacing organics with water: Macromolecular engineering of non-water miscible poly(meth)acrylates via interfacial and ion-pair catalysis SARA ATRP in miniemulsion | 2023 |
9 | P. Chmielarz; I. Zaborniak | How we can improve ARGET ATRP in an aqueous system: Honey as an unusual solution for polymerization of (meth)acrylates | 2023 |
10 | P. Chmielarz; I. Zaborniak | Polymer-modified regenerated cellulose membranes: following the atom transfer radical polymerization concepts consistent with the principles of green chemistry | 2023 |
11 | P. Chmielarz; M. Flejszar; A. Hochół | Advances and opportunities in synthesis of flame retardant polymers via reversible deactivation radical polymerization | 2023 |
12 | P. Chmielarz; M. Flejszar; K. Ślusarczyk | From non-conventional ideas to multifunctional solvents inspired by green chemistry: fancy or sustainable macromolecular chemistry? | 2023 |
13 | P. Chmielarz; M. Flejszar; M. Oszajca | Red is the new green: Dry wine-based miniemulsion as eco-friendly reaction medium for sustainable atom transfer radical polymerization | 2023 |
14 | P. Chmielarz; M. Flejszar; M. Sroka; M. Sroka; I. Zaborniak | Innowacyjne koncepcje syntezy polimerów technikami polimeryzacji rodnikowej z przeniesieniem | 2023 |
15 | P. Chmielarz; M. Korbecka; K. Matyjaszewski; Z. Michno; I. Zaborniak | Vegetable Oil as a Continuous Phase in Inverse Emulsions: ARGET ATRP for Synthesis of Water-Soluble Polymers | 2023 |
16 | P. Chmielarz; M. Sroka; I. Zaborniak | Modification of Polyurethanes by Atom Transfer Radical Polymerization and Their Application | 2023 |
17 | P. Chmielarz; T. Pacześniak; K. Rydel-Ciszek; A. Sobkowiak | Bio-Inspired Iron Pentadentate Complexes as Dioxygen Activators in the Oxidation of Cyclohexene and Limonene | 2023 |
18 | M. Bockstaller; P. Chmielarz; T. Liu; K. Matyjaszewski; M. Sun; G. Szczepaniak; J. Tarnsangpradit; Y. Wang; Z. Wang; H. Wu; R. Yin; I. Zaborniak; Y. Zhao | Miniemulsion SI-ATRP by Interfacial and Ion-Pair Catalysis for the Synthesis of Nanoparticle Brushes | 2022 |
19 | P. Błoniarz; P. Chmielarz; K. Surmacz | Coffee Beverage: A New Strategy for the Synthesis of Polymethacrylates via ATRP | 2022 |
20 | P. Chmielarz; A. Górska; G. Grześ; K. Matyjaszewski; K. Pielichowska; Z. Wang; K. Wolski; I. Zaborniak | Maltotriose-based star polymers as self-healing materials | 2022 |
21 | P. Chmielarz; E. Ciszkowicz; K. Lecka-Szlachta; A. Macior; J. Smenda; K. Wolski; I. Zaborniak | A New Protocol for Ash Wood Modification: Synthesis of Hydrophobic and Antibacterial Brushes from the Wood Surface | 2022 |
22 | P. Chmielarz; H. Cölfen; M. Flejszar; M. Gießlb; J. Smenda; K. Wolski; S. Zapotoczny | A new opportunity for the preparation of PEEK-based bone implant materials: From SARA ATRP to photo-ATRP | 2022 |
23 | P. Chmielarz; I. Zaborniak | Comestible curcumin: From kitchen to polymer chemistry as a photocatalyst in metal-free ATRP of (meth)acrylates | 2022 |
24 | P. Chmielarz; I. Zaborniak | Nanofibers for the paper industry | 2022 |
25 | P. Chmielarz; M. Flejszar; A. Gennaro; A. Isse; M. Oszajca; K. Ślusarczyk; K. Wolski; M. Wytrwal-Sarna | Working electrode geometry effect: A new concept for fabrication of patterned polymer brushes via SI-seATRP at ambient conditions | 2022 |
26 | P. Chmielarz; M. Flejszar; M. Oszajca; J. Smenda; K. Ślusarczyk; K. Wolski; M. Wytrwal-Sarna | SI-ATRP on the lab bench: A facile recipe for oxygen-tolerant PDMAEMA brushes synthesis using microliter volumes of reagents | 2022 |
27 | P. Chmielarz; M. Sroka; I. Zaborniak | Lemonade as a rich source of antioxidants: Polymerization of 2-(dimethylamino)ethyl methacrylate in lemon extract | 2022 |
28 | K. Rydel-Ciszek | The most reactive iron and manganese complexes with N-pentadentate ligands for dioxygen activation—synthesis, characteristics, applications | 2021 |
29 | M. Caceres Najarro; P. Chmielarz; J. Iruthayaraj; A. Macior; I. Zaborniak | Lignin-based thermoresponsive macromolecules via vitamin-induced metal-free ATRP | 2021 |
30 | P. Chmielarz; A. Macior; I. Zaborniak | Smart, Naturally-Derived Macromolecules for Controlled Drug Release | 2021 |
31 | P. Chmielarz; A. Macior; J. Smenda; K. Wolski; I. Zaborniak | Hydrophobic modification of fir wood surface via low ppm ATRP strategy | 2021 |
32 | P. Chmielarz; A. Miłaczewska; T. Pacześniak; K. Rydel-Ciszek; A. Sobkowiak | ‘Oxygen-Consuming Complexes’–Catalytic Effects of Iron–Salen Complexes with Dioxygen | 2021 |
33 | P. Chmielarz; I. Zaborniak | Riboflavin-mediated radical polymerization – Outlook for eco-friendly synthesis of functional materials | 2021 |
34 | P. Chmielarz; M. Flejszar; J. Smenda; K. Wolski | Following principles of green chemistry: Low ppm photo-ATRP of DMAEMA in water/ethanol mixture | 2021 |
35 | P. Chmielarz; M. Flejszar; K. Ślusarczyk | Less is more: A review of μL-scale of SI-ATRP in polymer brushes synthesis | 2021 |
36 | P. Błoniarz; P. Chmielarz; T. Pacześniak; K. Rydel-Ciszek; A. Sobkowiak; K. Surmacz; I. Zaborniak | Iron-Based Catalytically Active Complexes in Preparation of Functional Materials | 2020 |
37 | P. Chmielarz; A. Macior; I. Zaborniak | Stimuli-Responsive Rifampicin-Based Macromolecules | 2020 |
38 | P. Chmielarz; I. Zaborniak | Dually-functional riboflavin macromolecule as a supramolecular initiator and reducing agent in temporally-controlled low ppm ATRP | 2020 |
39 | P. Chmielarz; I. Zaborniak | Miniemulsion switchable electrolysis under constant current conditions | 2020 |
40 | P. Chmielarz; K. Matyjaszewski; I. Zaborniak | Synthesis of riboflavin-based macromolecules through low ppm ATRP in aqueous media | 2020 |
41 | P. Chmielarz; K. Surmacz | Low ppm atom transfer radical polymerization in (mini)emulsion systems | 2020 |
42 | P. Chmielarz; K. Surmacz; I. Zaborniak | Synthesis of sugar-based macromolecules via sono-ATRP in miniemulsion | 2020 |
43 | P. Chmielarz; K. Wolski; I. Zaborniak | Riboflavin-induced metal-free ATRP of (meth)acrylates | 2020 |
44 | P. Chmielarz; M. Flejszar | Surface modifications of poly(ether ether ketone) via polymerization methods – current status and future prospects | 2020 |
45 | P. Chmielarz; M. Flejszar; G. Grześ; K. Wolski; S. Zapotoczny | Polymer Brushes via Surface-Initiated Electrochemically Mediated ATRP: Role of a Sacrificial Initiator in Polymerization of Acrylates on Silicon Substrates | 2020 |
46 | P. Chmielarz; M. Flejszar; K. Surmacz; I. Zaborniak | Triple-functional riboflavin-based molecule for efficient atom transfer radical polymerization in miniemulsion media | 2020 |
47 | P. Chmielarz; M. Flejszar; R. Ostatek; K. Surmacz; I. Zaborniak | Preparation of hydrophobic tannins-inspired polymer materials via low ppm ATRP methods | 2020 |
48 | P. Chmielarz; M. Martinez; K. Matyjaszewski; Z. Wang; K. Wolski; I. Zaborniak | Synthesis of high molecular weight poly(n-butyl acrylate) macromolecules via seATRP: From polymer stars to molecular bottlebrushes | 2020 |
49 | P. Chmielarz; A. Gennaro; G. Grześ; A. Isse; A. Sobkowiak; K. Wolski; I. Zaborniak; S. Zapotoczny | Tannic acid-inspired star-like macromolecules via temporally-controlled multi-step potential electrolysis | 2019 |
50 | P. Chmielarz; I. Zaborniak | Temporally-controlled ultrasonication-mediated atom transfer radical polymerization in miniemulsion | 2019 |
51 | P. Chmielarz; I. Zaborniak | Ultrasound-mediated atom transfer radical polymerization (ATRP) | 2019 |
52 | P. Chmielarz; K. Matyjaszewski; I. Zaborniak | Modification of wood-based materials by atom transfer radical polymerization methods | 2019 |
53 | P. Chmielarz; M. Flejszar | Surface-initiated atom transfer radical polymerization for the preparation of well-defined organic-inorganic hybrid nanomaterials | 2019 |