The aim of studying and bibliography

The main aim of study: The student obtains knowledge of the basics of Bioprocess Engineering, including the theory of heat and mass transport. Then he learns to apply both theories to the units taught in the subject of unit processes of Bioprocess Engineering. The student learns the mechanisms of bioengineering processes, methods of their mathematical modeling and optimal conduct.

The general information about the module: The module is implemented on the fifth and sixth semester. In sem. 5 the module includes 30 hours.L, 15 hours. Exc.; 15 hours. L.;In sem. 6 the module includes 15 hours L.,15 hours. Ex. Semester 5 ends with a credit. Semester 6 ends with an exam. The lecture is supported by blackboard exercises, where the practical application of the theory is shown on task examples, and also a laboratory, where practical methods of experimental research on unit processes and the interpretation of experimental data are shown.

Bibliography required to complete the module

Bibliography used during lectures

1	T. Hobler	Ruch ciepła i wymienniki	WNT W-wa.	1986
2	T. Hobler	Dyfuzyjny ruch masy i absorbery	WNT W-wa.	1976
3	M. Serwiński	Zasady inżynierii chemicznej i procesowej	WNT W-wa.	1982
4	Praca zbior. pod red. Z Ziółkowskiego	Procesy dyfuzyjne i termodynamiczne, cz. I; II; III	skrypt Pol. Wrocławskiej.	1980
5	D. Antos, K.Kaczmarski, W. Piątkowski	Wymiana ciepła	Mat. Pom. Of. Wyd. PRz.	2012
6	K. Kaczmarski, W. Piątkowski	Ruch masy	Mat. pom. Of. Wyd. PRz.	2014
7	D. Antos, W. Piątkowski	Procesy dyfuzyjne	Mat. pom. Of. Wyd. PRz.	2014
8	D. Antos, W. Piątkowski	Procesy równoczesnego ruchu ciepła i masy	Mat. pom. Of. Wyd. PRz.	2014

Bibliography used during classes/laboratories/others

1	R. Zarzycki	Zadania rachunkowe z Inżynierii Chemicznej	PWN Łódź.	1980
2	Praca zbiorowa pod red. J. Bandrowskiego i M. Palicy	Materiały pomocnicze do ćwiczeń i projektów z Inżynierii chemicznej	Wyd. Pol. Śl.	2005
3	Z. Kawala; M.M. Pająk; J. Szust; T. Kudra	Zbiór zadań z podstawowych procesów Inżynierii Chemicznej	skrypt Pol. Wrocławskiej cz.: II oraz III.	1979
4	K.F. Pawłow; P.G. Romankow; A.A. Noskow	Przykłady i zadania z zakresu aparatury i inżynierii chemicznej	Wydawnictwa Naukowo-Techniczne.	1981
5	T. Kudra (pod redakcją)	Zbiór zadań z podstaw teoretycznych inżynierii chemicznej i procesowej	WNT W-wa.	1985
6	praca zbiorowa pod red. PRz	Inżynieria Chemiczna Laboratorium	Of. Wyd. PRz.	1998
7	J. Bandrowski, L. Troniewski	Destylacja i rektyfikacja	PWN W-wa.	1980

Bibliography to self-study

1	Z. Ziółkowski	Ekstrakcja w przemyśle chemicznym	WNT W-wa.	1980
2	S. Bredsznajder	Własności gazów i cieczy	WNT W-wa.	1962
3	R. Petrus, G. Aksielrud, J. Gumnicki, W. Piątkowski	Wymiana masy w układzie ciecz-ciało stałe	Of. Wyd. PRz.	1998

Basic requirements in category knowledge/skills/social competences

Formal requirements: Registration for the sem. V and VI

Basic requirements in category knowledge: Knowlegde on applied mathematics, physical chemistry, chemical thermodynamics

Basic requirements in category skills: 1. Basic konwledge in the area of: phsysics, mathematics, phsysical chemistry, informatics 2. Ability to learn from textbooks, lecture notes, to make out lecture notes 3. Ability to solve problems

Basic requirements in category social competences: Ability to intellectual work in the group

Module outcomes

MEK	The student who completed the module	Types of classes / teaching methods leading to achieving a given outcome of teaching	Methods of verifying every mentioned outcome of teaching	Relationships with KEK	Relationships with PRK
01	Student acquires knowledge of theoretical foundations of heat motion and diffusive mass motion.	problem lecture, table exercises; problem exercises; problem lab.	the exam written part, colloquium	K_W10++ K_W18++ K_U12+ K_K01+	P6S_KK P6S_KR P6S_UW P6S_WG
02	Student based on the basic theories of processes, ie. heat transfer, mass transfer taught describe the basic processes of separation of mixtures, including biological mixtures.	problem lecture; table exercises; problem lab	Exam: written part, colloquium	K_W10+ K_W18+ K_U12+ K_K01+	P6S_KK P6S_KR P6S_UW P6S_WG
03	Student can separate the mixture by means of extraction, distillation, rectification, absorption.	problem lecture; table exercises; problem lab	Exam: written part, colloquium	K_W10++ K_W18++ K_U12+ K_K01+	P6S_KK P6S_KR P6S_UW P6S_WG
04	Student knows the mechanisms of engineering processes and the methods of their mathematical modeling and optimal conduct.	problem lecture; table exercises; problem lab	Exam: written part, colloquium	K_W10++ K_W18+++	P6S_WG

Attention: Depending on the epidemic situation, verification of the achieved learning outcomes specified in the study program, in particular credits and examinations at the end of specific classes, can be implemented remotely (real-time meetings).

The syllabus of the module

Sem.	TK	The content	realized in	MEK
5	TK01	Heat Transfer: Kinds of the Heat Transfer: Thermal Conduction, I-St Fourier Law, Thermal Conduction Coefficient, Heat Non- And Conductors, Thermal Conduction Across Wall, Heat Transfer Resistance, Heat Convection – Newton Equation, Heat Transfer Cases, Criterial Numbers And Equations, Heat Radiation, Heat Screen Meaning, Heat Losses to Environment, Overall Heat Transfer, Newton Equation for Overall Heat Transfer, Overall Heat Transfer Coefficient, Basis Of Heat Exchanger Design.	W1-W14, C1-C7	MEK01 MEK02 MEK04
5	TK02	Mass Transfer: Mass Diffusion, I-St Fick Law, Mass Diffusion Coefficients, Mass Transfer Resistance, Kinds of the Mass Diffusion, Mass Diffusion, Mass Convection, Newton Kinetic Equation, Mass Transfer Cases, Criterial Numbers And Equations, Overall Mass Transfer, Newton Equation for Overall Mass Transfer, Overall Mass Transfer Coefficient, Disappearance of Mass Transfer Resistance, Overall Mass Transfer Driving Force, Basis Of Mass Exchanger Design. Absorption; A) Process Definition, B) Static’s of the Process – Absorption Equilibrium, Kinds of the Equilibrium Line Notations, C) Process Kinetics, Mass and Overall Mass Transport in the Absorption, D) Mass Balance of the Absorption, Operation Line of the Absorption, Minimum of the Spraying Liquid Mass and Velocity, E) Overall Mass Transfer Driving Force in Absorption, F) Chemisorption.	W15-W30, C8-C15	MEK01 MEK02 MEK03 MEK04
6	TK01	Distillation And Rectification: Points A) to F) Analogous to the Same Above with the Following Differences: Distillation Equilibrium for Binary Component System, Kinds of the Equilibrium Line Notations - for Ideal System – Raoult Law, Nonideal Systems – Aberrations From Raoult Law, Azeotropes, Differential Distillation, Equilibrium Distillation, Mass and Overall Mass Transport in the Rectification, Batch Rectification, Continuous Rectification, Heat and Mass Balances of the Rectification, Heat and Mass Balances of the Operated Plate, Operation Lines of the Rectification, Minimum and Maximum Minimum of the Column Reflux	W1-W7, C1-C7, L1-L8	MEK02 MEK03 MEK04
6	TK02	Extraction: Points A) to F) Analogous to the Same Above with the Following Differences: Extraction Equilibrium for Ternary Component System, Ideal System – Nernst Law, Nonideal Systems – Aberrations From Nernst Law, Stepping Extraction Parallel-Current and Counter-Current Extraction, Minimum and Maximum of the Extrahent Mass, Kinds of the Mathematics Solution of the Mentioned Above Extraction Cases, Column Extraction.	W8-W15, C8-C15, L9-L15	MEK02 MEK03 MEK04

The student's effort

The type of classes	The work before classes	The participation in classes	The work after classes
Lecture (sem. 5)	The preparation for a test: 7.00 hours/sem.	contact hours: 30.00 hours/sem.	complementing/reading through notes: 5.00 hours/sem. Studying the recommended bibliography: 5.00 hours/sem.
Class (sem. 5)	The preparation for a Class: 2.00 hours/sem. The preparation for a test: 5.00 hours/sem.	contact hours: 15.00 hours/sem.	Finishing/Studying tasks: 5.00 hours/sem.
Advice (sem. 5)	The preparation for Advice: 1.00 hours/sem.	The participation in Advice: 1.00 hours/sem.
Credit (sem. 5)	The preparation for a Credit: 5.00 hours/sem.	The written credit: 5.00 hours/sem.
Lecture (sem. 6)	The preparation for a test: 5.00 hours/sem.	contact hours: 15.00 hours/sem.	complementing/reading through notes: 5.00 hours/sem. Studying the recommended bibliography: 2.00 hours/sem.
Class (sem. 6)	The preparation for a Class: 4.00 hours/sem. The preparation for a test: 4.00 hours/sem.	contact hours: 15.00 hours/sem.	Finishing/Studying tasks: 3.00 hours/sem.
Laboratory (sem. 6)	The preparation for a Laboratory: 2.00 hours/sem. The preparation for a test: 1.00 hours/sem.	contact hours: 15.00 hours/sem.	Finishing/Making the report: 2.00 hours/sem.
Advice (sem. 6)	The preparation for Advice: 1.00 hours/sem.	The participation in Advice: 1.00 hours/sem.
Exam (sem. 6)	The preparation for an Exam: 5.00 hours/sem.

The way of giving the component module grades and the final grade

The type of classes	The way of giving the final grade
Lecture	Passing the Lecture - OW: Factor related to the term Course test OW / Credit w=1 - 1-st term; w=0.9 - 2-nd term; w=0.8 - 3rd term. w=0.8 - 3-rd term;
Class	Excercises are taken as seminar. The mark in the excercises on the base 1 test points - OC.
The final grade	Final mark receives a credit for a course in Bioprocess Eng. - sem (5) - according to formula: Sem. 5: OK = 0,7 OW + 0,3 OC
Lecture	Passing the Lecture = evaluation in an exam. Factor related to the term Exam / Credit w=1 - 1-st term; w=0.9 - 2-nd term; w=0.8 - 3rd term. w=0.8 - 3-rd term;
Class	Excercises are taken as seminar. The mark in the excercises on the base 1 test - OC. rules as in sem. 5
Laboratory	Laboratories – exercises performed by a group under the supervision of an academic teacher. Passing the laboratory based on the grade from the colloquium - OL. The condition for passing the laboratory is also the correct preparation of reports from all exercises.
The final grade	Final mark in an exam for a course in Bioprocessing.- sem (6) - according to formula: Sem. 6: OK = 0,65 OE + 0,2 OC + 0,15 OL

Sample problems

Required during the exam/when receiving the credit
(-)

Realized during classes/laboratories/projects
(-)

Others
(-)

Can a student use any teaching aids during the exam/when receiving the credit : yes

Available materials : In the credits of exercises: YES J. Bandrowski. M. Palica, "Materiały pomocnicze do ćwiczeń i i projektów z Inżynierii chemicznej"; During the exam; NO

The contents of the module are associated with the research profile: yes

1	D. Antos; I. Poplewska; P. Zimoch	Dissociation events during processing of monoclonal antibodies on strong cation exchange resins	2022
2	D. Antos; A. Bajek-Bil; M. Balawejder; M. Olbrycht; W. Piątkowski; I. Poplewska	Development of a Route to the Most Active Nafronyl Stereoisomer by Coupling Asymmetric Synthesis and Chiral Chromatography Separation	2021
3	D. Antos; W. Piątkowski; I. Poplewska	A case study of the mechanism of unfolding and aggregation of a monoclonal antibody in ion exchange chromatography	2021
4	D. Antos; M. Balawejder; H. Lorenz; M. Olbrycht; W. Piątkowski; I. Poplewska; A. Seidel-Morgenstern	Cooperative Kinetic Model to Describe Crystallization in Solid Solution Forming Systems	2019
5	D. Antos; M. Kołodziej; A. Łyskowski; W. Piątkowski; I. Poplewska; P. Szałański	Determination of protein crystallization kinetics by a through-flow small-angle X-ray scattering method	2019