Cycle of education: 2022/2023
The name of the faculty organization unit: The faculty Chemistry
The name of the field of study: Pharmaceutical engineering
The area of study: technical/biological sciences
The profile of studing:
The level of study: first degree study
Type of study: full time
discipline specialities :
The degree after graduating from university: Bachelor of Science (BSc)
The name of the module department : Department of Inorganic and Analytical Chemistry
The code of the module: 12685
The module status: mandatory for teaching programme
The position in the studies teaching programme: sem: 3 / W30 L30 / 5 ECTS / E
The language of the lecture: Polish
The name of the coordinator 1: Prof. Tomasz Ruman, DSc, PhD, Eng.
The name of the coordinator 2: Maria Misiorek, PhD
semester 3: Joanna Nizioł, DSc, PhD , office hours Tuesday 10:00-12:00, Thursday 9:00-11:00
The main aim of study: To acquaint students with basic information in the field of biochemistry on the characteristics of biologically important molecules and biochemical processes.
The general information about the module: Includes 30 lecture hours and 30 laboratory hours ending with an exam.
1 | John L. Tymoczko , Jeremy M. Berg | Biochemistry: A Short Course | W.H.Freeman & Co Ltd. | 2015 |
2 | Berg J.M., Tymoczko J.L., Stryer L. | Biochemia | Wydawnictwo Naukowe PWN, Warszawa. | 2011 |
3 | Doonan S. | Białka i peptydy | Wydawnictwo Naukowe PWN. | 2008 |
4 | Nelson D.L., Cox M.M. | Lehninger Principles of Biochemistry | W. H. Freeman and Company. | 2008 |
1 | Kłyszejko-Stefanowicz L., red. | Ćwiczenia z biochemii. | Wydawnictwo Naukowe PWN, Warszawa. | 2013 |
1 | Hames D.B., Hooper N.M. | Biochemia: krótkie wykłady | Wydawnictwo Naukowe PWN, Warszawa. | 2010 |
2 | Tymoczko J.L., Berg J.M., Stryer L. | Biochemia: krótki kurs | Wydawnictwo Naukowe PWN, Warszawa. | 2013 |
3 | Turner P.C. et al. | Krótkie wykłady: Biologia Molekularna | Wydawnictwo Naukowe PWN, Warszawa. | 2002 |
Formal requirements: Registration for the semester.
Basic requirements in category knowledge: Basic knowledge of cell biology and general, inorganic and organic chemistry
Basic requirements in category skills: Ability to independently search and interpret scientific information. Ability to work in laboratory under the supervision.
Basic requirements in category social competences: Ability to work as a part of a team during search and interpretation of scientific information. Ability to work in a team as a part of laboratory exercises under the supervision.
MEK | The student who completed the module | Types of classes / teaching methods leading to achieving a given outcome of teaching | Methods of verifying every mentioned outcome of teaching | Relationships with KEK | Relationships with PRK |
---|---|---|---|---|---|
01 | Student knows the chemical nature of the main classes of biological compounds: amino acids, peptides, proteins, carbohydrates and lipids. | lecture, laboratory | Written exam, Colloquium |
K_W02++ K_W03++ K_W08+ K_U01++ K_U15++ K_K01+++ |
P6S_KK P6S_UK P6S_UU P6S_UW P6S_WG |
02 | Understands the complexity and interdependence of processes in living organisms. | Lecture |
K_W01++ K_W02+++ K_U01++ K_U15++ |
P6S_UK P6S_UU P6S_UW P6S_WG |
|
03 | StudentHe knows basic transformations and biochemical pathways occurring in living systems. | lecture | written exam |
K_W08++ K_W09+ |
P6S_WG |
04 | The student is able to identify the examined compound | laboratory exercises |
K_W01++ K_W02++ K_U01++ K_U07+ K_U10++ |
P6S_UK P6S_UW P6S_WG |
|
05 | Understands the importance of the process of learning and improving professional qualifications in the field of professional qualifications and updating directional knowledge. | lecture, laboratory exercises | written exam, colloquium |
K_U15++ K_K01+++ |
P6S_KK P6S_UU |
Attention: Depending on the epidemic situation, verification of the achieved learning outcomes specified in the study program, in particular credits and examinations at the end of specific classes, can be implemented remotely (real-time meetings).
Sem. | TK | The content | realized in | MEK |
---|---|---|---|---|
3 | TK01 | W01 | MEK02 MEK05 | |
3 | TK02 | W02-W06 | MEK01 MEK05 | |
3 | TK03 | W07 | MEK01 MEK05 | |
3 | TK04 | W08 | MEK01 MEK05 | |
3 | TK05 | W9 | MEK01 MEK05 | |
3 | TK06 | W10-W15 | MEK01 MEK02 MEK03 MEK05 | |
3 | TK07 | L01-L06 | MEK01 MEK04 MEK05 |
The type of classes | The work before classes | The participation in classes | The work after classes |
---|---|---|---|
Lecture (sem. 3) | The preparation for a test:
6.00 hours/sem. |
contact hours:
30.00 hours/sem. |
complementing/reading through notes:
5.00 hours/sem. Studying the recommended bibliography: 20.00 hours/sem. |
Laboratory (sem. 3) | The preparation for a Laboratory:
6.00 hours/sem. The preparation for a test: 12.00 hours/sem. |
contact hours:
30.00 hours/sem. |
Finishing/Making the report:
6.00 hours/sem. |
Advice (sem. 3) | The preparation for Advice:
2.00 hours/sem. |
The participation in Advice:
2.00 hours/sem. |
|
Exam (sem. 3) | The preparation for an Exam:
20.00 hours/sem. |
The written exam:
1.00 hours/sem. |
The type of classes | The way of giving the final grade |
---|---|
Lecture | The mark is issued on the basis of the result of a written examination. |
Laboratory | The assessment shall be based on an average of six colloquia. The scores for each test: 3 points. - dst, 3.5 points. - dst+, 4 points. - db, 4.5 points. - db+, 5 pt. - db |
The final grade | The final grade in the module is the average of the grades from lectures and laboratory exercises: K=0.5*wA+0.5*wL (A-lectures, L-laboratories, w-factor taking into account the credit term: w=1.0 for the first term, w=0.9 for the second term, w=0.8 for the third term) such that K: 3.30 - dst (3.0), 3.31 - 3.75 - +dst (3.5), 3.76 - 4.25 - db (4.0), 4.26 - 4.70 - +db (4.5), 4.71 - bdb (5.0). The average can be drawn only if all the grades are positive. |
Required during the exam/when receiving the credit
(-)
Realized during classes/laboratories/projects
(-)
Others
(-)
Can a student use any teaching aids during the exam/when receiving the credit : no
1 | A. Kołodziej; Z. Krupa; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; A. Płaza-Altamer; T. Ruman | Untargeted metabolomics of bladder tissue using liquid chromatography and quadrupole time-of-flight mass spectrometry for cancer biomarker detection | 2024 |
2 | B. Guratowska; A. Kuźniar; J. Nizioł; A. Nowak; M. Okrasa; T. Ruman; M. Ryngajłło; J. Szulc | Uncontrolled Post-Industrial Landfill—Source of Metals, Potential Toxic Compounds, Dust, and Pathogens in Environment—A Case Study | 2024 |
3 | M. Misiorek; N. Pieńkowska; M. Siorek; Ż. Szymaszek; M. Twardowska; Ł. Uram; S. Wołowiec | Repurposed Drugs Celecoxib and Fmoc-L-Leucine Alone and in Combination as Temozolomide-Resistant Antiglioma Agents—Comparative Studies on Normal and Immortalized Cell Lines, and on C. elegans | 2024 |
4 | V. Copie; A. Kołodziej; Z. Krupa; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; A. Płaza-Altamer; T. Ruman; B. Tripet | Metabolomic profiling of human bladder tissue extracts | 2024 |
5 | Z. Krupa; M. Misiorek; J. Nizioł; T. Ruman | Infrared Laser-Based Selected Reaction Monitoring Mass Spectrometry Imaging of Banana (Musa spp.) Tissue—New Method for Detection and Spatial Localization of Metabolites in Food | 2024 |
6 | A. Arendowski; A. Kołodziej; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; A. Płaza-Altamer; T. Ruman | Monoisotopic silver nanoparticles-based mass spectrometry imaging of human bladder cancer tissue: Biomarker discovery | 2023 |
7 | A. Kołodziej; A. Nieczaj; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; A. Płaza-Altamer; T. Ruman | Untargeted urinary metabolomics for bladder cancer biomarker screening with ultrahigh-resolution mass spectrometry | 2023 |
8 | A. Kołodziej; Z. Krupa; J. Nizioł; A. Płaza-Altamer; T. Ruman | Infrared pulsed fiber laser-produced gold and silver-109 nanoparticles for laser desorption/ionization mass spectrometry of steroid hormones | 2023 |
9 | M. Dudek; B. Gutarowska; M. Komar; J. Nizioł; P. Nowicka-Krawczyk; T. Ruman | Biodeterioration potential of algae on building materials - Model study | 2023 |
10 | S. Kuberski; A. Kuźniar; J. Nizioł; A. Nowak; I. Nowak; M. Okrasa; T. Ruman; B. Szponar; J. Szulc | Biological and chemical contamination of illegal, uncontrolled refuse storage areas in Poland | 2023 |
11 | V. Copie; A. Kołodziej; A. Nieczaj; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; A. Płaza-Altamer; T. Ruman; B. Tripet | Targeted and untargeted urinary metabolic profiling of bladder cancer | 2023 |
12 | A. Kołodziej; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; A. Płaza-Altamer; T. Ruman | Untargeted ultra-high-resolution mass spectrometry metabolomic profiling of blood serum in bladder cancer | 2022 |
13 | A. Kołodziej; J. Nizioł; A. Płaza-Altamer; T. Ruman | Infrared pulsed fiber laser-produced silver-109 nanoparticles for laser desorption/ionization mass spectrometry of 3-hydroxycarboxylic acids | 2022 |
14 | A. Kołodziej; J. Nizioł; A. Płaza-Altamer; T. Ruman | Infrared pulsed fiber laser-produced silver-109-nanoparticles for laser desorption/ionization mass spectrometry of amino acids | 2022 |
15 | A. Kołodziej; J. Nizioł; A. Płaza-Altamer; T. Ruman | Infrared pulsed fiber laser-produced silver-109-nanoparticles for laser desorption/ionization mass spectrometry of carboxylic acids | 2022 |
16 | A. Kołodziej; J. Nizioł; A. Płaza-Altamer; T. Ruman | Laser Ablation Synthesis in Solution and Nebulization of Silver-109 Nanoparticles for Mass Spectrometry and Mass Spectrometry Imaging | 2022 |
17 | A. Kołodziej; J. Nizioł; A. Płaza-Altamer; T. Ruman | Laser generated gold nanoparticles for mass spectrometry of low molecular weight compounds | 2022 |
18 | A. Kołodziej; J. Nizioł; A. Płaza-Altamer; T. Ruman | Obrazowanie tkanek za pomocą spektrometrii mas z laserową desorpcją/jonizacją | 2022 |
19 | B. Gutarowska; M. Komar; P. Konca; J. Nizioł; P. Nowicka-Krawczyk; T. Ruman | Metabolomic analysis of photosynthetic biofilms on building façades in temperate climate zones | 2022 |
20 | B. Gutarowska; T. Ruman; J. Szulc | Metagenomika i metabolomika – nowoczesne metody systemowe w identyfikacji mikroorganizmów oraz metabolitów odpowiedzialnych za niszczenie obiektów zabytkowych | 2022 |
21 | S. Kuberski; J. Nizioł; A. Nowak; M. Okrasa; T. Ruman; J. Szulc | Assessment of Physicochemical, Microbiological and Toxicological Hazards at an Illegal Landfill in Central Poland | 2022 |
22 | V. Copie; A. Kołodziej; J. Nizioł; K. Nogueira; L. Nogueira; A. Ossolińska; K. Ossoliński; T. Ossoliński; A. Płaza-Altamer; T. Ruman; B. Tripet | Metabolomic and elemental profiling of blood serum in bladder cancer | 2022 |
23 | A. Arendowski; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; T. Ruman | Serum and urine analysis with gold nanoparticle-assisted laser desorption/ionization mass spectrometry for renal cell carcinoma metabolic biomarkers discovery | 2021 |
24 | A. Arendowski; V. Copie; J. Nizioł; K. Nogueira; L. Nogueira; K. Ossoliński; T. Ruman; B. Tripet | Metabolomic and elemental profiling of human tissue in kidney cancer | 2021 |
25 | A. Arendowski; V. Copie; J. Nizioł; K. Ossoliński; T. Ruman; B. Tripet | Nuclear magnetic resonance and surface-assisted laser desorption/ionization mass spectrometry-based metabolome profiling of urine samples from kidney cancer patients | 2021 |
26 | A. Kołodziej; T. Ruman; J. Szulc | Silver-109/Silver/Gold Nanoparticle-Enhanced Target Surface-Assisted Laser Desorption/Ionisation Mass Spectrometry—The New Methods for an Assessment of Mycotoxin Concentration on Building Materials | 2021 |
27 | B. Gutarowska; K. Majchrzycka; J. Nizioł; A. Nowak; M. Okrasa; T. Ruman; M. Sulyok; B. Szponar; J. Szulc | Microbiological and Toxicological Hazards in Sewage Treatment Plant Bioaerosol and Dust | 2021 |
28 | I. Beech; A. Drążkowska; B. Guratowska; J. Karbowska-Berent; T. Ruman; J. Sunner; J. Szulc | Metabolomics and metagenomics analysis of 18th century archaeological silk | 2021 |
29 | M. Misiorek; J. Nizioł; T. Ruman | Zastosowanie spektometrii mas do obrazowania rozmieszczenia flawonoidów w owocu truskawki | 2021 |
30 | A. Arendowski; J. Nizioł; K. Ossoliński; T. Ruman | Gold nanostructures - assisted laser desorption/ionization mass spectrometry for kidney cancer blood serum biomarker screening | 2020 |
31 | A. Arendowski; J. Nizioł; K. Ossoliński; T. Ruman | Screening of Urinary Renal Cancer Metabolic Biomarkers with Gold Nanoparticles-assisted Laser Desorption/Ionization Mass Spectrometry | 2020 |
32 | A. Arendowski; V. Copie; J. Nizioł; K. Ossoliński; T. Ruman; B. Tripet | Nuclear magnetic resonance and surface-assisted laser desorption/ionization mass spectrometry-based serum metabolomics of kidney cancer | 2020 |
33 | A. Filipowicz-Rachwał; J. Markowicz; M. Misiorek; Ł. Uram; E. Wałajtys-Rode; S. Wołowiec | Celecoxib substituted biotinylated poly(amidoamine) G3 dendrimer as potential treatment for temozolomide resistant glioma therapy and anti-nematode agent | 2020 |
34 | A. Kołodziej; J. Nizioł; T. Ruman | Gold and silver nanoparticles-based laser desorption/ionization mass spectrometry method for detection and quantification of carboxylic acids | 2020 |
35 | B. Guratowska; J. Karbowska-Berent; T. Kozielec; T. Ruman; J. Szulc | Analyses of microorganisms and metabolites diversity on historic photographs using innovative methods | 2020 |
36 | B. Gutarowska; A. Jachowicz; S. Kowalska; W. Machnowski; T. Ruman; A. Steglinska; J. Szulc | Beeswax-Modified Textiles: Method of Preparation and Assessment of Antimicrobial Properties | 2020 |
37 | B. Gutarowska; I. Jablonskaja; E. Jabłońska; J. Karbowska-Berent; T. Ruman; J. Szulc | Metabolomics and metagenomics characteristic of historic beeswax seals | 2020 |
38 | E. Chmiel; A. Czerniecka-Kubicka; M. Misiorek; M. Pyda; P. Tutka; Ł. Uram; M. Walczak; S. Wołowiec | Stepwise glucoheptoamidation of poly(amidoamine) dendrimer G3 to tune physicochemical properties of the potential drug carrier: in vitro tests for cytisine conjugates | 2020 |
39 | I. Beech; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; A. Płaza; T. Ruman; J. Sunner | Localization of Metabolites of Human Kidney Tissue with Infrared Laser-Based Selected Reaction Monitoring Mass Spectrometry Imaging and Silver-109 Nanoparticle-Based Surface Assisted Laser Desorption/Ionization Mass Spectrometry Imaging | 2020 |
40 | T. Ruman; J. Szulc | Laser Ablation Remote-Electrospray Ionisation Mass Spectrometry (LARESI MSI) Imaging—New Method for Detection and Spatial Localization of Metabolites and Mycotoxins Produced by Moulds | 2020 |
41 | A. Arendowski; J. Kucharz; J. Nizioł; A. Ossolińska; K. Ossoliński; T. Ossoliński; T. Ruman; P. Wiechno | Mass spectrometry-based metabolomic profiling of prostate cancer-a pilot study | 2019 |
42 | A. Filipowicz-Rachwał; J. Markowicz; M. Misiorek; M. Pichla; Ł. Uram; E. Wałajtys-Rode; S. Wołowiec | The Effect of Biotinylated PAMAM G3 Dendrimers Conjugated with COX-2 Inhibitor (celecoxib) and PPARγ Agonist (Fmoc-L-Leucine) on Human Normal Fibroblasts, Immortalized Keratinocytes and Glioma Cells in Vitro | 2019 |
43 | A. Filipowicz-Rachwał; M. Misiorek; Ł. Uram; E. Wałajtys-Rode; A. Winiarz; S. Wołowiec | Synthesis and Different Effects of Biotinylated PAMAM G3 Dendrimer Substituted with Nimesulide in Human Normal Fibroblasts and Squamous Carcinoma Cells | 2019 |
44 | J. Cebulski; M. Kus-Liśkiewicz; T. Ruman; M. Stompor; D. Szmuc; K. Szmuc; Ł. Szyller; S. Wołowiec; I. Zawlik | Silver nanoparticles deposited on calcium hydrogenphosphate - silver phosphate matrix; biological activity of the composite | 2019 |
45 | M. Misiorek; J. Nizioł; T. Ruman | Mass spectrometry imaging of low molecular weight metabolites in strawberry fruit (Fragaria x ananassa Duch.) cv. Primoris with 109Ag nanoparticle enhanced target | 2019 |