The aim of studying and bibliography

The main aim of study: The main purpose of this subject is delivery knowledge and practical skills about analytical methods used in pharmaceutical industry.

The general information about the module: Unit is realized on the second term of course: Chemistry technology. Unit consists of 15 h of lecture and 30 h of laboratory . Examination finishes the unit.

Bibliography required to complete the module

Bibliography used during lectures

1	M. Jarosza	Nowoczesne techniki analityczne	PWN Warszawa .	2006
2	A. Cygański	Chemiczne metody analizy ilościowej	WNT.
3	E. R. Malinowski	Factor Analysis in Chemistry	Wydanie III, John Wiley and Sons, .	2002
4	A. Smilde, R. Bro, P. Geladi,	Multi-way Analysis.	John Wiley and Sons, (wybrane rozdzialy)..	2004
5	H. Mark, J. Workman J., Jr.	Chemometrics in Spectroscopy,	Elsevier Inc (wybrane rozdzialy)..	2007

Bibliography used during classes/laboratories/others

1

A. Smilde, R. Bro, P. Geladi

Multi-way Analysis.,

John Wiley and Sons, (wybrane rozdzialy)..

2004

Basic requirements in category knowledge/skills/social competences

Formal requirements: course of analytical chemistry, instrumental analysis and pharmaceutical analysis is finished by student

Basic requirements in category knowledge: One uses the chemistry calculations in the quantification analysis. Student knows the basic analytical techniques, like: chromatography, Uv-vis , IR and NMR spectroscopy, potentiometry, AAS spectrosc

Basic requirements in category skills: Student use the laboratory glass necessary in quality and quantification analysis, practices rules GLP. One can make oneself the basic analysis using analytical techniques, like: chromatography, Uv-

Basic requirements in category social competences: One co-operates and works in group, organizes and displays responsibility for work state. One is supposed to make the tasks according with suitable procedures. Student keeps attention during work wi

Module outcomes

MEK	The student who completed the module	Types of classes / teaching methods leading to achieving a given outcome of teaching	Methods of verifying every mentioned outcome of teaching	Relationships with KEK	Relationships with PRK
01	student knows the base of NIR spectroscopy and its application in pharmaceutical analysis.	lecture	written test	K_W01++ K_U15++	P7S_UW P7S_WG
02	one knows the application of derivative spectroscopy in the medicine analysis	lecture	written test	K_U14++	P7S_UW
03	student can analyse amount of water in the chemical reagents, can use the electrochemical methods in the analysis of active substances. One can analyse amount of metals using the AAS spectroscopy. One can interpret the spectra of medicines.	laboratory	report	K_U14+	P7S_UW
04	one keeps the fire regulations and BHP, student uses the protective clothing	laboratory	performance observation	K_U15+	P7S_UW
05	one is supposed to know the GMP rules and work in the team.	laboratory	performance observation	K_U15+	P7S_UW

Attention: Depending on the epidemic situation, verification of the achieved learning outcomes specified in the study program, in particular credits and examinations at the end of specific classes, can be implemented remotely (real-time meetings).

The syllabus of the module

Sem.	TK	The content	realized in	MEK
2	TK01	Principle and application of NIR spectroscopy in pharmaceutical analysis. A derivative spectroscopy in the medicine analysis. Factor analysis in chemistry. Advance techniques of mass spectrometry: ESI, MALDI, APCI ionization, MS/MS techniques.	W01-W07	MEK01 MEK02
2	TK02	Determination of metals by AAS spectroscopy – atomization in graphite tray (GF-AAS)	L01	MEK03 MEK04
2	TK03	Determination of acetylsalycilic acid and salycilic acid in medicine by derivative spectroscopy	L02	MEK03 MEK05
2	TK04	Determination of water by Karl-Fischer methods.	L03	MEK03 MEK04
2	TK05	Interpretation of IR, H-NMR and MS spectrums of medicines	L04	MEK03
2	TK06	Electrochemical determination of active substance of medicine	L05	MEK03 MEK04
2	TK07	Factor analysis in chemistry	L07	MEK03

The student's effort

The type of classes	The work before classes	The participation in classes	The work after classes
Lecture (sem. 2)		contact hours: 9.00 hours/sem.	complementing/reading through notes: 5.00 hours/sem. Studying the recommended bibliography: 10.00 hours/sem.
Laboratory (sem. 2)	The preparation for a Laboratory: 3.00 hours/sem. The preparation for a test: 5.00 hours/sem.	contact hours: 18.00 hours/sem.	Finishing/Making the report: 3.00 hours/sem.
Advice (sem. 2)
Exam (sem. 2)	The preparation for an Exam: 20.00 hours/sem.	The written exam: 2.00 hours/sem.

The way of giving the component module grades and the final grade

The type of classes	The way of giving the final grade
Lecture
Laboratory	pass mark for each exercise - OL
The final grade	The final note (OK) is calculated according to the formula: OK = 50% OW + 50% OL

Sample problems

Required during the exam/when receiving the credit
(-)

Realized during classes/laboratories/projects
(-)

Others
(-)

Can a student use any teaching aids during the exam/when receiving the credit : no

The contents of the module are associated with the research profile: yes

1	D. Naróg; A. Sobkowiak	Electrochemistry of Flavonoids	2023
2	P. Chmielarz; T. Pacześniak; K. Rydel-Ciszek; A. Sobkowiak	Bio-Inspired Iron Pentadentate Complexes as Dioxygen Activators in the Oxidation of Cyclohexene and Limonene	2023
3	Ł. Florczak; B. Kościelniak; A. Kramek; A. Sobkowiak	The Influence of Potassium Hexafluorophosphate on the Morphology and Anticorrosive Properties of Conversion Coatings Formed on the AM50 Magnesium Alloy by Plasma Electrolytic Oxidation	2023
4	D. Naróg; A. Sobkowiak	Electrochemical Investigation of some Flavonoids in Aprotic Media	2022
5	K. Darowicki; Ł. Florczak; G. Nawrat; K. Raga; J. Ryl; J. Sieniawski; A. Sobkowiak; M. Wierzbińska	The Effect of Sodium Tetrafluoroborate on the Properties of Conversion Coatings Formed on the AZ91D Magnesium Alloy by Plasma Electrolytic Oxidation	2022
6	A. Baran; M. Drajewicz; A. Dryzner; M. Dubiel; Ł. Florczak; M. Kocój-Toporowska; A. Krząkała; K. Kwolek; P. Kwolek; G. Lach; G. Nawrat; Ł. Nieużyła; K. Raga; J. Sieniawski; A. Sobkowiak; T. Wieczorek	Method of Forming Corrosion Resistant Coating and Related Apparatus	2021
7	P. Chmielarz; A. Miłaczewska; T. Pacześniak; K. Rydel-Ciszek; A. Sobkowiak	‘Oxygen-Consuming Complexes’–Catalytic Effects of Iron–Salen Complexes with Dioxygen	2021
8	D. Naróg	Electrochemical study of quercetin in the presence of galactopyranose: Potential application to the electrosynthesis of glycoconjugates of quinone/quinone methide of quercetin	2020
9	P. Błoniarz; P. Chmielarz; T. Pacześniak; K. Rydel-Ciszek; A. Sobkowiak; K. Surmacz; I. Zaborniak	Iron-Based Catalytically Active Complexes in Preparation of Functional Materials	2020
10	P. Chmielarz; A. Gennaro; G. Grześ; A. Isse; A. Sobkowiak; K. Wolski; I. Zaborniak; S. Zapotoczny	Tannic acid-inspired star-like macromolecules via temporally-controlled multi-step potential electrolysis	2019