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Protein engineering

Some basic information about the module

Cycle of education: 2022/2023

The name of the faculty organization unit: The faculty Chemistry

The name of the field of study: Biotechnology

The area of study: technical sciences

The profile of studing:

The level of study: first degree study

Type of study: full time

discipline specialities : Applied biochemistry, Purification and analysis of biotechnological products

The degree after graduating from university: Bachelor of Science (BSc)

The name of the module department : Department of Biochemistry and Bioinformatics

The code of the module: 10326

The module status: mandatory for the speciality Applied biochemistry

The position in the studies teaching programme: sem: 6 / W30 P15 / 4 ECTS / Z

The language of the lecture: Polish

The name of the coordinator: Andrzej Łyskowski, PhD, Eng.

office hours of the coordinator: Konsultacje w trybie zdalnym po wcześniejszym zgłoszeniu: Poniedziałek: 12:15 - 13:45; Czwartek: 12:15 - 13:45.

semester 6: Konrad Hus, PhD, Eng.

The aim of studying and bibliography

The main aim of study: Understanding and exploring all stages protein engineering necessary for acquiring biotechnological products with improved properties.

The general information about the module: The module is introduced in the 6th semester of the first degree/ undergraduate course as a mandatory module for all specialty.It is accomplished with 15 hours of lecture and 30 hours of laboratory work. It ends with an examination-based assessment.

others: Aktualna literatura naukowa

Bibliography required to complete the module
Bibliography used during lectures
1 Jeremy M. Berg, Lubert Stryer, John L. Tymoczko Biochemia WN. 2011
2 Agnieszka Kraj, Anna Drabik, Jerzy Silberring Proteomika i metabolomika WUW. 2010
3 Stanisław Ledakiewicz Inżynieria biochemiczna Wydawnictwo WNT. 2011,
4 Jin Xiong Podstawy bioinformatyki Wydawnictwo Uniwersytetu Warszawskiego . 2009
5 P.C. Turner et al. Krótkie wykłady: Biologia molekularna Wydawnictwo Naukowe PWN. 2001
6 B.D. Hames et al. Krótkie wykłady: Biochemia Wydawnictwo naukowe PWN. 2002
7 Sawn Doonan Białka i peptydy Wydawnictwo Naukowe PWN. 2008
8 Mariusz Jaskólski Krystalografia dla biologów Wydawnictwo naukowe UAM. 2010
Bibliography used during classes/laboratories/others
1 Jak dla wykładów .
Bibliography to self-study
1 Jak dla wykładów .

Basic requirements in category knowledge/skills/social competences

Formal requirements: Valid registration

Basic requirements in category knowledge: Basic knowledge of biochemistry and biocatalysis

Basic requirements in category skills: Self-education skills

Basic requirements in category social competences: Ability to work both alone and in a group

Module outcomes

MEK The student who completed the module Types of classes / teaching methods leading to achieving a given outcome of teaching Methods of verifying every mentioned outcome of teaching Relationships with KEK Relationships with PRK
01 Understands (i) molecular aspects of and (ii) kinetic aspect of enzyme operations lecture, project written test, project progress observation, project reports K_W05+
K_U03+
P6S_UK
P6S_WG
02 Knows current methods and strategies of enzyme modyfications lecture, project written test, project progress observation, project reports K_W03+
K_U03+
P6S_UK
P6S_WG
03 Is able to independently acquire knowledge lecture, project written test, project progress observation, project reports K_W14+
K_U03+
P6S_UK
P6S_WG
04 Can, on the basis of their knowledge, conduct the in-silico process of protein modification lecture written test K_U08+
K_U09+
P6S_UO
P6S_UW
05 Understands the need of improving their skills and knowledge resulting from the constantly expanding knowledge K_W12+
K_K02+
P6S_KO
P6S_KR
P6S_WG
06 Knows how to work in a group and individually, can make decisions and carry out the instructions of superiors project project progress observation, project reports K_U19+
K_K02+
P6S_KO
P6S_KR
P6S_UO
P6S_UW

Attention: Depending on the epidemic situation, verification of the achieved learning outcomes specified in the study program, in particular credits and examinations at the end of specific classes, can be implemented remotely (real-time meetings).

The syllabus of the module

Sem. TK The content realized in MEK
6 TK01 Molecular aspects of enzymatic activity W01-W05 MEK01 MEK03
6 TK02 Selected aspects of design and protein structural modifications W06-W10 MEK02 MEK03
6 TK03 Selected examples of protein engineering W11-W15 MEK03 MEK05
6 TK04 Protein engineering in-silico for the improvement of its biotechnological properties P01-P15 MEK04 MEK06

The student's effort

The type of classes The work before classes The participation in classes The work after classes
Lecture (sem. 6) contact hours: 30.00 hours/sem.
Studying the recommended bibliography: 5.00 hours/sem.
Project/Seminar (sem. 6) The preparation for projects/seminars: 20.00 hours/sem.
contact hours: 15.00 hours/sem..
Doing the project/report/ Keeping records: 20.00 hours/sem.
Advice (sem. 6)
Credit (sem. 6) The preparation for a Credit: 20.00 hours/sem.
The written credit: 2.00 hours/sem.

The way of giving the component module grades and the final grade

The type of classes The way of giving the final grade
Lecture
Project/Seminar
The final grade The final note is an derivaticve of all points collected from the module activities: K=a*wA+c*wC+l*wL (a-lecture coeff., c-tutorial coeff., l-laboratory/project coeff., w=1,0, w=0,9, w=0,8 receptively for the 1st, 2nd, 3rd attempt). The note is calculated only if all components have been passed. Values of coefficiants are presented to the students during the initial teaching session.

Sample problems

Required during the exam/when receiving the credit
(-)

Realized during classes/laboratories/projects
(-)

Others
(-)

Can a student use any teaching aids during the exam/when receiving the credit : no

The contents of the module are associated with the research profile: no