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Structural biology

Some basic information about the module

Cycle of education: 2022/2023

The name of the faculty organization unit: The faculty Chemistry

The name of the field of study: Biotechnology

The area of study: technical sciences

The profile of studing:

The level of study: second degree study

Type of study: full time

discipline specialities : Laboratory diagnostics in biotechnology, Pharmaceutical biotechnology, Process and bioprocess engineering, Purification and analysis of biotechnological products

The degree after graduating from university: Master of Science (MSc)

The name of the module department : Department of Biochemistry and Bioinformatics

The code of the module: 10246

The module status: mandatory for the speciality Pharmaceutical biotechnology

The position in the studies teaching programme: sem: 2 / W15 P20 / 3 ECTS / Z

The language of the lecture: Polish

The name of the coordinator: Karol Hęclik, PhD, Eng.

office hours of the coordinator: WT 0930-1130, SR 0930-1130

The aim of studying and bibliography

The main aim of study: Review of the selected aspects of analysis and usage of the information about structure of large biomolecules in understanding of biochemical and biotechnological processes.

The general information about the module: Module consists of 15 hours of lectures and 20 hours of project classes.

others: Aktualne publikacje naukowe z zakresu biotechnologii, biologii strukturalnej.

Bibliography required to complete the module
Bibliography used during lectures
1 Andreas Liljas, Lars Liljas, Jure Piskur, Goran Lindblom, Poul Nissen, Morten Kjelgaard Textbook of structural biology World Scientific Publishing Co. Pte. Ltd.. 2011
2 Gale Rhodes Crystallography Made Crystal Clear Academic Press. 2006

Basic requirements in category knowledge/skills/social competences

Formal requirements: Valid student registration.

Basic requirements in category knowledge: Knowledge of biochemistry, enzymology, physical chemistry.

Basic requirements in category skills: Ability to independently acquire and critically evaluate scientific information.

Basic requirements in category social competences: Ability to work individually and in team.

Module outcomes

MEK The student who completed the module Types of classes / teaching methods leading to achieving a given outcome of teaching Methods of verifying every mentioned outcome of teaching Relationships with KEK Relationships with PRK
01 Knows the structure and methods used to determine structure of large biomacromolecules. Lecture Written test K_W06+++
P7S_WG
02 is able to retrieve, visualize and analyse structural data for selected biomolecules. Lecture, individual/group project Written test, work progress monitoring, project presentation. K_W02+++
K_K02+++
P7S_KR
P7S_WG
03 Understands functions performed by selected biomolecules in progress and regulation of biological processes. Lecture, individual/group project Written test, project progress monitoring, project presentation K_W02+++
K_U02+++
P7S_UK
P7S_WG

Attention: Depending on the epidemic situation, verification of the achieved learning outcomes specified in the study program, in particular credits and examinations at the end of specific classes, can be implemented remotely (real-time meetings).

The syllabus of the module

Sem. TK The content realized in MEK
2 TK01 Introduction to structural biology (protein, nucleic acid, lipid bi-layers and enzyme structure). W01-03 MEK01
2 TK02 Methods used for determination of biomolecules. Molecular modeling: molecular mechanics. W04-06 MEK01
2 TK03 Molecular modeling: molecular dynamics. Retrieval and analysis of structural data. W07-09 MEK01 MEK02
2 TK04 Application of structural information in research and industrial practice. W10-12 MEK01 MEK03
2 TK05 Biomolecules structure and function prediction. W13-15 MEK01 MEK02 MEK03
2 TK06 Application of structural data in solution of selected biotechnological problem. P01-20 MEK01 MEK02 MEK03

The student's effort

The type of classes The work before classes The participation in classes The work after classes
Lecture (sem. 2) The preparation for a test: 8.00 hours/sem.
contact hours: 15.00 hours/sem.
complementing/reading through notes: 4.00 hours/sem.
Studying the recommended bibliography: 4.00 hours/sem.
Project/Seminar (sem. 2) The preparation for projects/seminars: 4.00 hours/sem.
contact hours: 20.00 hours/sem..
Doing the project/report/ Keeping records: 8.00 hours/sem.
The preparation for the presentation: 4.00 hours/sem.
Advice (sem. 2) The preparation for Advice: 2.00 hours/sem.
The participation in Advice: 2.00 hours/sem.
Credit (sem. 2) The preparation for a Credit: 8.00 hours/sem.
The written credit: 2.00 hours/sem.

The way of giving the component module grades and the final grade

The type of classes The way of giving the final grade
Lecture The note is issued to students who participated in all classes (in accordance with the Study Regulations) and who: passed the colloquium (for the full-time teaching mode) or who have completed and presented the elaboration of a selected problem in the form of a presentation (for the distance learning mode) in the form of a presentation. When assessing the grade, the substantive level of the presentation and activity during classes will be taken into account.
Project/Seminar Pass note is granted to the students who participated in all exercises and presented report based on performed exercises.
The final grade The final note is an average of all notes collected from the module: K=a*wA+c*wC+l*wL (a-lecture coeff., c-tutorial coeff., l-laboratory coeff., w=1,0, w=0,9, w=0,8 receptively for the 1st, 2nd, 3rd attempt). The note is calculated only if all components have been passed. Values of coefficients are presented to the students during the initial teaching session.

Sample problems

Required during the exam/when receiving the credit
(-)

Realized during classes/laboratories/projects
(-)

Others
(-)

Can a student use any teaching aids during the exam/when receiving the credit : no

The contents of the module are associated with the research profile: no